Samenvatting

STEPPED-CARE PREVENTS DEPRESSIVE AND ANXIETY DISORDERS IN VISUALLY IMPAIRED OLDER ADULTS

H.P.A. VAN DER AA, G.H.M.B. VAN RENS & R.M.A. VAN NISPEN

Objective of this study was to compare the effectiveness of steppedcare with usual care in visually impaired older adults (¨50 years) with subthreshold depression/anxiety. A single-masked multicentre randomised controlled trial was performed (n=265). Steppedcare contained: 1) watchful waiting, 2) cognitive behavioural therapy-based guided self-help, 3) problem solving treatment, and 4) referral to the general practitioner. The primary outcome was the 24-month cumulative incidence of depressive and anxiety disorders. Stepped-care signifi cantly reduced the incidence of disorders (relative risk .63; 95%CI .57 to .69), even if time to the event was taken into account (adjusted hazard ratio .57; 95%CI .35 to .93). The number needed to treat was 5.8. It is concluded that stepped-care seems to be a promising way to deal with depression and anxiety in visually impaired older adults. (Trial registration: http://www. trialregister.nl, identifier: NTR3296.)


1306 Weergaven
4 Downloads
Log in
Eén op de drie visueel beperkte oudere volwassenen ervaart klachten van depressie en/of angst. Dit is twee keer zo veel als in de algemene bevolking. Een nieuw ontwikkelde stepped-care interventie blijkt effectief in het voorkomen van depressie en angststoornissen in deze populatie, zo blijkt uit onderzoek van Hilde van der Aa en collega’s. Deze interventie bestaat uit vier stappen die oplopen in intensiteit: 1) ‘watchful waiting’, 2) een zelfhulpcursus gebaseerd op cognitieve gedragstherapie, 3) ‘problem solving treatment’ en 4) een verwijzing naar de huisarts.

Introductie

Volgens de World Health Organization (WHO, 2010) zijn wereldwijd ongeveer 285 miljoen mensen visueel beperkt, van wie 65 procent vijftig jaar of ouder is. Klachten van depressie en angst komen veel voor bij visueel beperkte oudere volwassenen. Ongeveer een derde van hen ervaart subklinische klachten van depressie en/of angst (Augustin et al., 2007; Evans, Fletcher & Wormald, 2007; Lotery et al., 2007; Van der Aa et al., 2015a)1111924. Zeven procent heeft een daadwerkelijke angststoornis (Van der Aa et al., 2015a), en vijf tot zeven procent heeft een depressieve stoornis volgens de DSM-IV (Brody et al., 2001; Horowitz, Reinhardt & Kennedy, 2005; Van der Aa et al., 2015a)713. Deze percentages zijn substantieel hoger dan de prevalentie in de algemene oudere bevolking (Beekman, Copeland & Prince, 1999; Bryant, Jackson & Ames, 2008)28.

Zowel depressie als angst worden geassocieerd met een aanzienlijke ziektelast. Zij kunnen al in een subklinisch stadium leiden tot een

Literatuurlijst

  1. Augustin, A., Sahel, J.A., Bandello, F., Dardennes, R., Maurel, F., Negrini, C. et al. (2007). Anxiety and depression prevalence rates in age-related macular degeneration. Invest Ophthalmol.Vis.Sci., 48, 1498-1503.
  2. Beekman, A.T., Copeland, J.R. & Prince, M.J. (1999). Review of community prevalence of depression in later life. Br.J.Psychiatry, 174, 307-311.
  3. Beekman, A.T., Deeg, D.J., van Limbeek, J., Braam, A.W., De Vries, M.Z. & van Tilburg, W. (1997). Criterion validity of the Centre for Epidemiologic Studies Depression scale (CES-D): results from a community-based sample of older subjects in The Netherlands. Psychol.Med., 27, 231-5.
  4. Binns, A.M., Bunce, C., Dickinson, C., Harper, R., Tudor-Edwards, R., Woodhouse, M. et al. (2012). How Effective is Low Vision Service Provision? A Systematic Review. Survey of Ophthalmology, 51, 34-65.
  5. Bjelland, I., Dahl, A.A., Haug, T.T. & Neckelmann, D. (2002). The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J.Psychosom.Res., 52, 69-77.
  6. Breslau, N. (1985). Depressive symptoms, major depression, and generalized anxiety: a comparison of self-reports on CES-D and results from diagnostic interviews. Psychiatry Res., 15, 219-29.
  7. Brody, B.L., Gamst, A.C, Williams, R.A., Smith, A.R., Lau, P.W., Dolnak, D. et al. (2001). Depression, visual acuity, comorbidity, and disability associated with age-related macular degeneration. Ophthalmology, 108, 1893-1900.
  8. Bryant, C., Jackson, H. & Ames, D. (2008). The prevalence of anxiety in older adults: methodological issues and a review of the literature. J.Affect.Disord., 109, 233-250.
  9. Callahan, C.M., Unverzagt, F.W., Hui, S.L., Perkins, A.J. & Hendrie, H.C. (2002). Six-item screener to identify cognitive impairment among potential subjects for clinical research. Med.Care, 40, 771-81.
  10. Casten, R. & Rovner, B. (2013). Update on depression in age-related macular degeneration. Curr.Opin.Ophthalmol., 24, 239-243.
  11. Evans, J.R., Fletcher, A.E. & Wormald, R.P. (2007). Depression and anxiety in visually impaired older people. Ophthalmology, 114, 283-288.
  12. Hakkaart-van Roijen, L. (2002). Manual Trimbos/iMTA questionnaire for Costs associated with Psychiatric Illness (TiC-P). Institute for Medical Technology Assessment, Erasmus University Medical Centre. Rotterdam, the Netherlands.
  13. Horowitz, A., Reinhardt, J.P. & Kennedy, G.J. (2005). Major and subthreshold depression among older adults seeking vision rehabilitation services. Am.J.Geriat.Psychiatry, 13, 180-7.
  14. Horowitz, A., Reinhardt, J.P. & Raykov, T. (2007). Development and validation of a short-form adaptation of the Age-related Vision Loss scale: The AVL12. J.Visual Impairment Blindness, 101, 146-159.
  15. Hutschemaekers, G.J.M. (2003). Multidisciplinary guidelines in Dutch mental health care: plans, bottlenecks and possible solutions. Int.J.Integr. Care, 3, e10.
  16. Jones, G.C., Rovner, B.W., Crews, J.E. & Danielson, M.L. (2009). Effects of depressive symptoms on health behavior practices among older adults with vision loss. Rehabil.Psychol., 54, 164-172.
  17. Kok, I. & van Wijngaarden, B. (2003). Client Appreciation in Mental Health Care: Manual of the Dutch Mental Healthcare Thermometer of Appreciation by Clients. Trimbos-instituut/GGZ. Utrecht, the Netherlands.
  18. Lamers, L.M., Stalmeier, P F., McDonnell, J., Krabbe, P.F. & Van Busschbach, J.J. (2005). Measuring the quality of life in economic evaluations: the Dutch EQ-5D tariff. Ned.Tijdschr.Geneeskd., 149, 1574-8.
  19. Lotery, A., Xu, X., Zlatava, G. & Loftus, J. (2007). Burden of illness, visual impairment and health resource utilisation of patients with neovascular age-related macular degeneration: results from the UK cohort of a five-country cross-sectional study. Br.J.Ophthalmol., 91, 1303-7.
  20. Meadows, G., Harvey, C., Fossey, E. & Burgess, P. (2000). Assessing perceived need for mental health care in a community survey: development of the Perceived Need for Care Questionnaire (PNCQ). Soc. Psychiatry.Psychiatr.Epidemiol., 35, 427-435.
  21. Mykletun, A., Stordal, E. & Dahl, A.A. (2001). Hospital Anxiety and Depression (HAD) scale: factor structure, item analyses and internal consistency in a large population. Br.J.Psychiatry, 179, 540-544.
  22. National Institute for Health and Clinical Excellence NICE (2014). Depression in adults with a chronic physical health problem. Accessed on 5 December 2014, from http://www.nice.org.uk/guidance/cg91.
  23. Sheehan, D. V., Lecrubier, Y., Sheehan, K.H., Amorim, P., Janavs, J., Weiller, E., et al. (1998). The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J.Clin.Psychiatry, 59, 22-33.
  24. Van der Aa, H.P.A., Comijs, H.C., Penninx, B.W.J.H., Van Rens, G.H.M.B. & Van Nispen, R.M.A. (2015). Major depressive and anxiety disorders in visually impaired older adults. Invest.Ophth.Vis.Sci., 56, 849-854.
  25. Van der Aa, H.P.A., Hoeben, M., Rainey, L., Van Rens, G.H.M.B., Vreeken, H.L. & Van Nispen, R.M.A. (2015). Why visually impaired older adults often do not receive mental health services: the patient’s perspective. Qual.Life.Res., 24, 969-978.
  26. Van der Aa, H.P.A., Van Rens, G.H.M.B., Comijs, H.C., Bosmans, J.E., Margrain, T.H. & Van Nispen, R.M. (2013). Stepped-care to prevent depression and anxiety in visually impaired older adults – design of a randomised controlled trial. BMC Psychiatry, 13, 209.
  27. Van Nispen, R.M.A., Knol, D.L., Langelaan, M. & Van Rens, G.H.M.B. (2011). Re-evaluating a vision-related quality of life questionnaire with item response theory (IRT) and differential item functioning (DIF) analyses. BMC Med.Res.Methodol., 11, 125.
  28. Van Nispen, R.M.A., Knol, D.L., Neve, H.J. & Van Rens G.H.M.B. (2010). A multilevel item response theory model was investigated for longitudinal vision-related quality-of-life data. J.Clin.Epidemiol., 63, 321-30.
  29. Van Rens, G.H.M.B., Vreeken, H.L. & Van Nispen, R.M.A. (2011). Guideline Vision Disorders: Rehabilitation and Referral. Accessed on 12 Nov 2014, from http://tinyurl.com/jmdxj9y.
  30. Van Straten, A., Hill, J., Richards, D.A. & Cuijpers, P. (2014). Stepped care treatment delivery for depression: a systematic review and meta-analysis. Psychol.Med., 45, 231-246.
  31. Van’t Veer-Tazelaar, P.J., van Marwijk, H.W., Van Oppen, P., van Hout, H.P., van der Horst, H.E., Cuijpers, P. et al. (2009). Stepped-care prevention of anxiety and depression in late life: a randomized controlled trial. Arch.Gen.Psychiatry, 66, 297-304.
  32. Van Vliet, I.M. & de Beurs, E. (2007). The MINI-International Neuropsychiatric Interview. A brief structured diagnostic psychiatric interview for DSM-IV and ICD-10 psychiatric disorders. Tijdschr.Psychiatr., 49, 393-7.
  33. World Health Organization (2010). Global data on visual impairments 2010. Accessed on 16 October 2015, from http://tinyurl.com/jsybt5m.